What is the true difference between deleting/erasing your iPhone on the phone or through iTunes on Mac?

So I know I probably can ask Apple but what is the true difference between deleting/erasing your phone on the phone or through iTunes on Mac? I have had this question for a while and kinda wanted to try Apple community so I can hopefully get a answer and see what this community is about😄😊

[Re-Titled By Moderator]